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Scientific publications on Aphanizomenon flos-aquae

  • Jensen GS, Ginsberg DI, Huerta P, Citton M, Drapeau C (2000) Consumption of Aphanizomenon flos aquae has rapid effects on the circulation and function of immune cells in humans. A novel approach to nutritional mobilization of the immune system. JANA vol. 2 (3): 50-58. (Read abstract)

  • Kushak RI, Drapeau C, Van Cott EM, Winter HH (2000) Favorable effects of blue-green algae Aphanizomenon flos-aquae on rat plasma lipids. JANA vol. 2 (3): 59-65.
    (Read abstract)

  • Drapeau C, Aphanizomenon Flos-Aquae and the Nervous System, Attention Deficit Disorder, Depression and Mood Elevation (Read abstract)

  • Lahitova N, Doupovcova M, Zvonar J, Chandoga J, Hocman G (1994) Antimutagenic properties of fresh-water blue-green algae. Folia Microbiol (Praha), 39(4), pp. 301-3. (Read abstract)


  • Rafail I. Kushak, PhD, Dr Sc, Christian Drapeau MS and Harland S. Winter, MD (2001) The Effect of Blue-Green Algae Aphanizomenon Flos-Aquae on Nutrient Assimilation in Rats. 35 Jana Vol. 3, No. 4, 37 Jana Vol. 3, No. 4, 39 Jana Vol. 3, No. 4. (Read Abstract.)

  • Gabriel Cousens, M.D. (1985) Report of Treatment of Alzheimer's Disease with Alphanae Klamathomenon Flos-Aqua. ORTHOMEDICINE Volume VIII, Number 1& 2. (Read Abstract.)


Scientific publications on nutrients found in Aphanizomenon flos-aquae:

Phycocyanin

  • Romay C, Armesto J, Remirez D, Gonzalez R, Ledon N, Garcia I (1998) Antioxidant and anti-inflammatory properties of C-phycocyanin from blue-green algae. Inflamm. Res. 47: 36-41. (Read abstract)

  • Romay C, Ledon N, Gonzalez R (1998) Further studies on anti-inflammatory activity of phycocyanin in some animal models of inflammation. Inflamm Res. 47(8):334-8. (Read abstract)

  • Gonzalez R, Rodriguez S, Romay C, Ancheta O, Gonzalez A, Armesto J, Remirez D, Merino N (1999) Anti-inflammatory activity of phycocyanin extract in acetic acid-induced colitis in rats. Pharmacol Res 39(1):55-9. (Read abstract)

  • Vadiraja BB, Gaikwad NW, Madyastha KM (1998) Hepatoprotective effect of C-phycocyanin: protection for carbon tetrachloride and R-(+)-pulegone-mediated hepatotoxicty in rats. Biochem Biophys Res Commun 249(2):428-31. (Read abstract)

  • C. Madhava Reddy, Vadiraja B. Bhat, G. Kiranmai, M. Narsa Reddy, P. Reddanna, and K. M. Madyastha (2000) Selective Inhibition of Clclooxygenase-2 by C-Phycocyanin, a Biliprotein from Spirulina platensis. Biochemical and Biophysical Research Communications 277, 599-603. (Read Abstract.)


  • Vadiraja B. Bhat and K. M. Madystha (2000) C-Phycocyanin: A Potent Peroxyl Radical Scavenger in Vivo and in Vitro. Biochemical and Biophysical Research Communications 275, 20-25. (Read Abstract.)
  • Cheyla Romay, Nuris Ledón, and Ricardo González (2000) Effects of Phycocyanin Extract on Prostaglandin E2 Levels in Mouse Ear Inflammation Test. Arzneim.-Forsch./Drug Research 50 (II), Nr 12, 1106-1109. (Read Abstract.)

  • Cheyla Romay, Nuris Ledón and Ricardo González. (1999) Letter to the Editor. Phycocyanin Extract Reduces Leukotriene B4 Levels in Arachidonic Acid-induced Mouse-ear Inflammation Test. J. Pharm. Pharmacol., 51: 641-642. (Read Abstract.)


  • Cheyla Romay and Richardo González (2000) Letter to the Editor. Phycocyanin is an Antioxidant Protector of Human Erythrocytes Against Lysis by Peroxyl Radicals. J. Pharm. Pharmacol., 52:
    367-368. (Read Abstract.)


  • Diadelis Remirez, Addys Gonzáles, Nelson Merino, Ricardo González, Odelsa Ancheta, Cheyla Romay and Sandra Rodrigues (1999) Research Article. Effect of Phycocyanin in Zymosan-Induced Arthritis in Mice-Phycocyanin as an Antiarthritic Compound. Drug Development Research, 48: 70-75.
    (Read Abstract.)

  • Victor Rimbau, Antoni Camins, David Pubill, Francese X. Sureda, Cheyla Romay, Ricardo González, Andrés Jimenéz, Elena Escubedo, Jordi Camarasa and Mercé Pallás (2001) Original Article. C-Phycocyanin protects cerebellar granule cells from low potassium/serum deprivation-induced apoptosis. Naunyn-Schmiedeberg's Arch Pharmacol, 364: 96-104. (Read Abstract.)
  • Victor Rimbau, Antoni Camins, Cheyla Romay, Ricardo Gonzáles and Merce Pallas (1999) Neuroscience Letters. Protective effects of C-phycocyanin against kainic acid-induced neuronal damage in rat hippocampus. Elsevier Science, 276: 75-78. (Read Abstract.)


    Natural Killer Cells


  • Nirmal Pugh, Samir A. Ross, Hala N. ElSohly, Mahmoud A. ElSohly and David S. Pasco (2001) Isolation of Three High Molecular Weight Polysaccharide Preparations with Potent Immunostimulatory Activity from Spirulina platensis, Aphanizomemon flos-aquae and Chlorella pyrenoidosa. Planta Med 67: 737-742. (Read Abstract.)



  • N. Pugh and D. S. Pasco (2001) Characterization of human monocyte activation by a water soluble preparation of Aphanizomenon flos-aquae. Phytomedicine, Vol. 8(6): 445-453. (Read Abstract.)

Phenylethylamine (PEA)


• A. Szabo, E. Billett and J. Turner (2001) Phenylethylamine, a possible link to the antidepressant effects of exercise? Br J Sports Med 35: 342-343. (Read Abstract.)

 

• Glen B. Baker, PhD, DSc; Ronald T. Coutts, PhD, DSc; and Andrew J. Greenshaw, PhD (2000) Journal of Psychiatry and Neuroscience. Neurochemical and metabolic aspects of antidepressants: an overview. J Psychiatry Neurosci, 25 (5): 481-496. (Read Abstract)

Other Extracts

  • Ø. Østensvik, O. M. Skulberg, B. Underdal and V. Hormazabal (1998) Antibacterial properties of extracts from selected planktonic freshwater cyanobacteria – a comparative study of bacterial bioassays. Journal of Applied Microbiology, 84, 1117-1124. (Read Abstract.)
  • David J. Schaeffer and Victor S. Krylov (2000) Anti-HIV Activity of Extracts and Compounds from Algae and Cyanobacteria. Ecotoxicology and Environmental Safety 45, 208-227 Environmental Research, Section B. (Read Abstract.)

Chlorophyll

  • Dashwood R, Negishi T, Hayatsu H, Breinholt V, Hendricks J, Bailey G. (1998) Chemopreventive properties of chlorophylls towards aflatoxin B1: a review of the antimutagenicity and anticarcinogenicity data in rainbow trout. Mutat Res. 399(2):245-53. Review. (Read abstract)

  • Chernomorsky S, Segelman A, Poretz RD. (1999) Effect of dietary chlorophyll derivatives on mutagenesis and tumor cell growth. Teratog Carcinog Mutagen.19(5):313-22. (Read abstract)

Carotenoids

  • Mayne ST. (1996) Beta-carotene, carotenoids, and disease prevention in humans. FASEB J. 10(7):690-701. (Read abstract)

  • Shaish, A., Daugherty, A., O'Sullivan, F., Schonfeld, G., and Heinecke, J.W. (1995) Beta-carotene inhibits atherosclerosis in hypercholesterolemic rabbits. J Clin Invest 96:2075-2082. (Read abstract)

  • Pryor WA, Stahl W, Rock CL (2000) Beta carotene: from biochemistry to clinical trials. Nutr Rev 58(2 Pt 1):39-53. (Read abstract)

  • Wang XD, Russell RM. Procarcinogenic and anticarcinogenic effects of beta-carotene. Nutr Rev 57(9 Pt 1):263-72. (Read abstract)

  • Tavani A, La Vecchia C (1999) Beta-carotene and risk of coronary heart disease. A review of observational and intervention studies. Biomed Pharmacother 53(9):409-16. (Read abstract)

  • Garewal, HS, et al., (1995) Emerging role of beta-carotene and antioxidant nutrients in prevention of oral cancer, Archives of Otolaryngology 121(2):141-144. (Read abstract)

Polyunsaturated fatty acids

  • Oomen CM, Feskens EJ, Rasanen L, Fidanza F, Nissinen AM, Menotti A, Kok FJ, Kromhout D. (2000) Fish consumption and coronary heart disease mortality in Finland, Italy and The Netherlands. Am J Epidemiol. 151(10):999-1006. (Read abstract)

  • von Schacky C. (2000) n-3 fatty acids and the prevention of coronary atherosclerosis. Am J Clin Nutr. 71(1 Suppl):224S-7S. (Read abstract)

  • Bruinsma KA, Taren DL. (2000) Dieting, essential fatty acid intake, and depression. Nutr Rev. 58(4):98-108. (Read abstract)

  • Edwards R, Peet M, Shay J, Horrobin D. (1998) Omega-3 polyunsaturated fatty acid levels in the diet and in red blood cell membranes of depressed patients. J Affect Disord. 48(2-3):149-55. (Read abstract)

  • Burgess JR, Stevens L, Zhang W, Peck L (2000) Long-chain polyunsaturated fatty acids in children with attention-deficit hyperactivity disorder. Am J Clin Nutr 71(1 Suppl):327S-30S. (Read abstract)

  • Ziboh VA, Miller CC, Cho Y. (2000) Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites. Am J Clin Nutr. 71(1 Suppl):361S-6S. (Read abstract)

  • Ziboh VA. (1989) Implications of dietary oils and polyunsaturated fatty acids in the management of cutaneous disorders. Arch Dermatol. 125(2):241-5 (Read abstract)

  • Goodfellow J, Bellamy MF, Ramsey MW, Jones CJ, Lewis MJ. (2000) Dietary supplementation with marine omega-3 fatty acids improve systemic large artery endothelial function in subjects with hypercholesterolemia. J Am Coll Cardiol 35(2):265-70. (Read abstract)

  • Calder PC (1998) Immunoregulatory and anti-inflammatory effects of n-3 polyunsaturated fatty acids. Braz J Med Biol Res 31(4):467-90. (Read abstract)